Watch Intently (one)darunavir will raise the level or effect of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
amifostine boosts effects of sildenafil by additive vasodilation. Use Caution/Check. Sildenafil has systemic vasodilatory properties and should additional lower blood pressure in clients taking antihypertensive prescription drugs.
Circumstances of sudden minimize or lack of hearing, which can be accompanied by tinnitus and dizziness, are actually noted in temporal Affiliation with the use of PDE-5 inhibitors, together with sildenafil citrate. In several of the instances, health care conditions and other elements have been reported which will have performed a job.
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erythromycin stearate will raise the amount or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Consider a starting dose of 25 mg in sufferers dealt with with erythromycin.
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इस दवा का उपयोग करने से पहले गर्भवती महिलाओं को डॉक्टर से परामर्श करना चाहिए
diltiazem will improve the amount or effect of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
primidone will lower the level or effect of sildenafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Keep get more info away from or Use Alternate Drug. Potent CYP3A4 inducers are predicted to trigger considerable decreases in sildenafil plasma concentrations
At doses increased as opposed to suggested twenty mg TID, there was a bigger incidence of some adverse reactions which include flushing, diarrhea, myalgia and Visible disturbances. Visible disturbances had been discovered as mild and transient, and were being predominately colour-tinge to vision, but also increased sensitivity to gentle or blurred eyesight.
erythromycin base will enhance the amount or effect of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Consider a commencing dose of twenty five mg in sufferers handled with erythromycin.
bosentan will lessen the extent or effect of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Powerful CYP3A4 inducers are predicted to trigger substantial decreases in sildenafil plasma stages